Many common neurological disorders, such as Parkinson’s disease, stroke and multiple sclerosis, are caused by a loss of neurons and glial cells. In recent years, neurons and glia have been generated successfully from stem cells in culture, fuelling efforts to develop stem-cell-based transplantation therapies for human patients. More recently, efforts have been extended to stimulating the formation and preventing the death of neurons and glial cells produced by endogenous stem cells within the adult central nervous system. The next step is to translate these exciting advances from the laboratory into clinically useful therapies.
in response to a request from a follower for stem cells and their use in treating Parkinson’s.
Members from my laboratory are working to improve the ability of grafted stems cells to find and formed synapses with their target, using a mouse model.
Read the transcript or watch the video for Dr Clare Parish.